Ebola Survivor Could Have Began Newest Outbreak — 5 Years Later

A brand new, preliminary genetic evaluation means that the present Ebola outbreak in Guinea might have originated with a survivor of the 2014-2016 West African Ebola outbreak, moderately than from an animal-to-human transmission.

In line with the pre-print report, the outbreak doubtless began with the survivor infecting a sexual accomplice with the lethal virus by semen — after the virus lay dormant within the man for a minimum of 5 years.

The evaluation, posted on-line Friday, was performed by scientists from Guinea, the Institut Pasteur in Senegal, the College of Nebraska Medical Heart, the College of Edinburgh, and the corporate PraesensBio.

In line with the Infectious Ailments Society of America (IDSA), the longest an Ebola survivor was believed to have shed the virus was about 500 days.

The earlier Ebola outbreak resulted in 28,000 instances and 11,000 deaths, primarily in Guinea, Liberia, and Sierra Leone, in response to the brand new report. The present outbreak in Guinea has resulted in 18 instances and has killed 9 individuals, in response to The New York Occasions.

The news is “sobering,” mentioned William Schaffner, MD, a communicable illness epidemiologist and pandemic preparedness professional at Vanderbilt College in Nashville.

“Who would have thought that the Ebola virus could remain latent in a person — a male — for 5 years and then set off another outbreak?” Schaffner mentioned. “Until this news came in, I think we all thought this latest Ebola outbreak was a consequence of an introduction from an animal species.”

“This gives a whole new public health resonance to the notion that male Ebola survivors are a potential reservoir of this infection for many years,” he mentioned.

Schaffner mentioned that the testes, along with the eye and the central nervous system, are areas within the physique the place the Ebola virus is thought to cover.

Widespread Vaccination?

The brand new report raises the query, he mentioned, about whether or not among the previous outbreaks in Africa weren’t launched from the wild however as a substitute occurred as a result of a survivor initiated the an infection in a accomplice.

The actual hazard of the virus mendacity dormant within the testes, moderately than the eye or within the nervous system, is that it could possibly be transmitted to somebody sexually, Schaffner mentioned.


The findings within the genetic evaluation may exacerbate the stigma for survivors, he mentioned.

It additionally raises the query about whether or not widespread vaccinations are wanted in equatorial Africa, he mentioned.

Moreover, though Ebola vaccines are very efficient, he mentioned, it is not recognized how lengthy they may defend individuals.

One other public well being measure could also be selling extra condom use, he mentioned, which comes with its personal set of difficulties.

In mild of this newest news, male survivors will transfer into the analysis highlight, Schaffner mentioned, and volunteers will probably be requested to offer semen specimens to search out out whether or not this can be a one-time occasion or one thing that occurs generally.

Michael Ryan, MD, government director of the World Well being Group (WHO) Well being Emergencies Programme, mentioned in a briefing on Friday that the WHO has despatched greater than 30,000 vaccine doses to the nation.

Medscape Medical News



Virological.org: “Guinea 2021 EBOV outbreak.”

Medical Infectious Ailments: “Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days.”

The New York Occasions: “Ebola Survivor Infected Years Ago May Have Started New Outbreak.”

William Schaffner, MD, Vanderbilt College, Nashville.

Michael Ryan, MD, government director, World Well being Group Well being Emergencies Programme.

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